KEGG   Rattus norvegicus (rat): 24296
Entry
24296             CDS       T01003                                 
Symbol
Cyp1a1
Name
(RefSeq) cytochrome P450 1A1
  KO
K07408  cytochrome P450 family 1 subfamily A1 [EC:1.14.14.1]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00140  Steroid hormone biosynthesis
rno00380  Tryptophan metabolism
rno00830  Retinol metabolism
rno00980  Metabolism of xenobiotics by cytochrome P450
rno01100  Metabolic pathways
rno04913  Ovarian steroidogenesis
rno05204  Chemical carcinogenesis - DNA adducts
rno05207  Chemical carcinogenesis - receptor activation
rno05208  Chemical carcinogenesis - reactive oxygen species
rno05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    24296 (Cyp1a1)
  09105 Amino acid metabolism
   00380 Tryptophan metabolism
    24296 (Cyp1a1)
  09108 Metabolism of cofactors and vitamins
   00830 Retinol metabolism
    24296 (Cyp1a1)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    24296 (Cyp1a1)
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    24296 (Cyp1a1)
 09160 Human Diseases
  09161 Cancer: overview
   05204 Chemical carcinogenesis - DNA adducts
    24296 (Cyp1a1)
   05207 Chemical carcinogenesis - receptor activation
    24296 (Cyp1a1)
   05208 Chemical carcinogenesis - reactive oxygen species
    24296 (Cyp1a1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    24296 (Cyp1a1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:rno00199]
    24296 (Cyp1a1)
Enzymes [BR:rno01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.1  unspecific monooxygenase
     24296 (Cyp1a1)
Cytochrome P450 [BR:rno00199]
 Cytochrome P450, animal type
  CYP1 family
   24296 (Cyp1a1)
SSDB
Motif
Pfam: p450
Other DBs
NCBI-GeneID: 24296
NCBI-ProteinID: NP_036672
RGD: 2458
Ensembl: ENSRNOG00000019500
UniProt: P00185
Position
8:66991940..66998014
AA seq 524 aa
MPSVYGFPAFTSATELLLAVTTFCLGFWVVRVTRTWVPKGLKSPPGPWGLPFIGHVLTLG
KNPHLSLTKLSQQYGDVLQIRIGSTPVVVLSGLNTIKQALVKQGDDFKGRPDLYSFTLIA
NGQSMTFNPDSGPLWAARRRLAQNALKSFSIASDPTLASSCYLEEHVSKEAEYLISKFQK
LMAEVGHFDPFKYLVVSVANVICAICFGRRYDHDDQELLSIVNLSNEFGEVTGSGYPADF
IPILRYLPNSSLDAFKDLNKKFYSFMKKLIKEHYRTFEKGHIRDITDSLIEHCQDRRLDE
NANVQLSDDKVITIVFDLFGAGFDTITTAISWSLMYLVTNPRIQRKIQEELDTVIGRDRQ
PRLSDRPQLPYLEAFILETFRHSSFVPFTIPHSTIRDTSLNGFYIPKGHCVFVNQWQVNH
DQELWGDPNEFRPERFLTSSGTLDKHLSEKVILFGLGKRKCIGETIGRLEVFLFLAILLQ
QMEFNVSPGEKVDMTPAYGLTLKHARCEHFQVQMRSSGPQHLQA
NT seq 1575 nt   +upstreamnt  +downstreamnt
atgccttctgtgtatggattcccagccttcacatcagccacagagctgctcctggccgtc
accacattctgccttggattctgggtggttagagtcacaagaacctgggttcccaaaggt
ctgaagagtccacccggaccctggggcttgcccttcatagggcacgtgctgaccctgggg
aagaacccacacctgtcactgacaaaactgagtcagcagtatggggacgtgctgcagatc
cgtattggctccacacccgtggtggtgctgagcggcctgaacaccatcaagcaggccctg
gtgaaacagggggatgacttcaaaggccggccagacctctacagcttcacacttatcgct
aatggccagagcatgactttcaacccagactctggaccgctgtgggctgcccgccggcgc
ctggcccagaatgcgctgaagagtttctccatagcctcagacccaacactggcatcctct
tgctacttggaagagcacgtgagcaaagaggctgaatacttaatcagcaagttccagaag
ctgatggcagaggttggccacttcgaccctttcaagtatttggtggtgtcagtggccaat
gtcatctgtgccatatgctttggcagacgttatgaccacgatgaccaagagctgctcagc
atagtcaatctaagcaatgagtttggggaggttactggttctggatacccagctgacttc
attcctatcctccgttacctccctaactcttccctggatgccttcaaggacttgaataag
aagttctacagtttcatgaagaagctaatcaaagagcactacaggacatttgagaagggc
cacatccgggacatcacagacagcctcattgagcattgtcaggacaggaggctggacgag
aatgccaatgtccagctctcagatgataaggtcattacgattgtttttgacctctttgga
gctgggtttgacacaatcacaactgctatctcttggagcctcatgtacctggtaaccaac
cctaggatacagagaaagatccaggaggagttagacacagtgattggcagggatcggcag
ccccggctttctgacagacctcagctgccctatctggaggccttcatcctggagaccttc
cgacattcatcctttgtcccattcaccatcccccacagcaccataagagatacaagtctg
aatggcttctatatccccaagggacactgtgtctttgtgaaccagtggcaggttaaccat
gaccaggaactatggggtgatccaaacgagttccggcctgaaaggtttcttacctccagt
ggcactctggacaaacacctgagtgagaaggtcattctctttggtttgggcaagcgaaag
tgcattggggagaccattggccgactggaggtctttctcttcctggccatcttgctgcag
caaatggaatttaatgtgtcaccaggcgagaaggtggatatgactcctgcctatgggctg
actttaaaacatgcccgctgtgagcacttccaagtgcagatgcggtcttctggtcctcag
catctccaggcttag

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (10)   
   KEGG PATHWAY (10)   
Chemical substance (43)   
   KEGG COMPOUND (43)   
Chemical reaction (22)   
   KEGG ENZYME (1)   
   KEGG REACTION (21)   
Genome (1)   
   KEGG GENOME (1)   
Gene (7)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   NAGAHAMA-S (1)   
   OC (1)   
   RGD (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (8)   
   RefSeq(nuc) (2)   
   GenBank (3)   
   EMBL (3)   
Protein domain (1)   
   Pfam (1)   
All databases (99)   

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